The use of neonicotinoids have been linked recently to causing honey bee kills through pesticide drift. This research will estimate baseline tolerance between strains of honeybees to several neonicotinoids by conducting diet incorporated bioassays. In addition, we are going to quantify residual insecticides in hive components by liquid chromatography equipped with a tandem mass spectrometer in 60 apiaries in Missouri (Summer 2016) to improve best management practices for beekeeping.